Gout, uric acid, and risk of death

Gout affects an estimated 4% of the population, or around 1 in 25 people.  Evidence suggests this number is growing and is certainly affecting a larger demographic than in the past.  A lot of confusion has surrounded the specifics on how high levels of uric acid may affect the heart and kidneys, even when acute Gout attacks are not present.

There have been studies attempting to separate the mortality rates of those with other risk factors, namely cardiovascular disease and diabetes, from those with just Gout and/or high uric acid levels.  The findings seem to suggest that Gout and high uric acid levels are independently responsible for higher death rates across most age, sex, and race subgroups independent of other pre-existing conditions.  The University in Limerick found those with the high serum uric acid levels displayed at 77% higher risk of death from all causes, and a 209% higher risk of cardiovascular death.  While pre-existing conditions such as obesity, hypertension, diabetes, etc. are strongly associated with a higher death risk, the results did not decrease by much when those factors were removed.

What does this mean for the Gout sufferer?  Continue reading “Gout, uric acid, and risk of death”

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