Cardiovascular Disease and Gout
The prevalence of cardiovascular disease continues to rise and is among the leading cause of mortality in the world. Inflammatory conditions such as Rheumatoid Arthritis and Gout are often associated with a higher risk and earlier onset of this disease. Research links gout to an increased risk of several types of cardiovascular disease, including heart attack, heart failure, and atrial fibrillation, or an irregular heartbeat. Epidemiological, experimental, and clinical data show that patients with hyperuricemia SUA are at increased risk of cardiac, renal, and vascular damage and CV events. Continue reading “Does Gout Increase The Cardiovascular Disease Risk Factor?”
Medical News Today: It is safe for people to walk with gout. In fact, doing joint friendly activities such as walking can help improve gout-related pain.
Gout is a form of arthritis that usually affects the big toe joint, but it can also affect the lesser toes, ankles, and knees. It normally affects one joint at a time.
People with gout may find it difficult to carry out physical activity, or they may be worried that physical activity will make their gout worse.
This article will examine whether or not it is safe to walk with gout. It will also cover how to manage, treat, and prevent this condition.
Continue reading “Is it OK to walk with gout?”
Largest ever study on subject uses data from more than 620,000 patients in UK health system
Date: August 28, 2019
Source:University of Limerick
Summary: Patients with gout are at increased risk of chronic kidney disease and kidney failure, according to new research.
Patients with gout are at increased risk of chronic kidney disease and kidney failure, according to new University of Limerick (UL), Ireland led research.
In one of the largest and most detailed studies ever conducted, patients recruited in general practice with a diagnosis of gout were more than twice as likely to develop kidney failure than those without, according to the study led by researchers at University of Limerick’s (UL) Graduate Entry Medical School (GEMS).
Continue reading “Gout ‘more than doubles’ risk of kidney failure”
Date:November 25, 2019
Source: California Institute of Technology
Summary: Scientists have developed an easier way to mass-produce highly sensitive sweat sensors that can detect a variety of low-concentration compounds related to health conditions.
There are numerous things to dislike about going to the doctor: Paying a copay, sitting in the waiting room, out-of-date magazines, sick people coughing without covering their mouths. For many, though, the worst thing about a doctor’s visit is getting stuck with a needle. Blood tests are a tried-and-true way of evaluating what is going on with your body, but the discomfort is unavoidable. Or maybe not, say Caltech scientists.
Continue reading “Wearable sweat sensor detects gout-causing compounds”
Let us better help you better understand this condition – despite the tons of misinformation that circulates on the internet.
Why are blood test results misleading when it comes to a Gout diagnosis?
Blood tests can reveal the concentration of uric acid in your system. However, while you are under an attack your blood could potentially read quite normal. Over 60% of patients presenting with acute gouty arthritis symptoms have uric acid levels of <8mg/dl. Measuring serum uric acid levels while under an attack may not be too helpful in a diagnostic sense. Why? The crystals relentlessly jabbing at your joints are NOT in a soluble form at that time.
Continue reading “Gout Questions and Answers”
We seem to have found ourselves at yet another set of crossroads regarding conflicting ideas when it comes to lab-grown foods such as the Impossible Burger. It may be easy to assume ‘plant-based’ diets are healthy, but are they? We know that highly processed foods are unhealthy and unfortunately this new fad of plant-based foods are exactly that, highly processed.
Continue reading “Gout Diet: Are Impossible Burgers/Foods Impossible To Be Good For You?”
ARTICHOKE POWDER (Globe Artichoke)
A relative of the hepatoprotective Milk Thistle, is popular for its pungent taste which is attributed to phytochemicals found in the green parts of the plants called cynaropicrin and cynarin, sesquiterpene lactones with documented medicinal actions. The phytochemicals in artichoke have been well documented and the leaves rather than the flower have been found to be higher in medicinal value.
Artichokes contain a very high antioxidant content, and in fact, contain two compounds (apigenin 7-rutinoside and narirutin) that are so unique they aren’t found in any other plant.
Traditional uses have included support for sluggish liver, poor digestion and atherosclerosis. Artichokes offer concentrated sources of amino acids and even help to support the natural growth of probiotics for the digestive system.
Continue reading “Artichoke Powder for Gout and Joint Health”
Considering that all disease occurs at the molecular and cellular level, could all disease share common causes and common solutions?
Toxic damage to cells leads to cellular death, and in large numbers can result in tissue and organ damage/failure. Some tissues and organs hold the capacity for self-repair, while others have no ability to regenerate. For example, the liver can repair damaged sections by fibrous replacement, whereas the nervous system tissue has no ability to regenerate itself. Of course, even the liver will have trouble if the damage is severe and/or continues to suffer from abuse.
Continue reading “Cell Death, Cellular Toxicity, and Gout”
TAK1 is an enzyme and signaling molecule in humans encoded by the MAP3K7 gene (a mitogen-activated protein). TAK1 regulates cellular death through various pathways. As we have discussed before, programmed cell death is a normal, physiologic process intended to help remove damaged cells. However, unattended cell death is the direct pathway for human disease. TAK1 contains binding proteins that are responsible for cell viability and tissue balance in a variety of organs.
TAK1 is a key molecular component that can readily determine of the fate of our body’s cells. TAK1 has been typically considered pro-survival, however, recent studies have determined that various factors could cause it to induce cell death. Scientifically speaking, studies are exploring the ability to inhibit TAK1 as a therapeutic approach to killing off rogue cancer cells and stopping chronic inflammatory response.
Continue reading “What is TAK1 and why is it important to inhibit its potentially destructive pathway?”