Gout: Genetics or Lifestyle Driven?

Genetic and genetic mutations can certainly play a role in disease, however, poor nutrition and a sedentary lifestyle can greatly increase the risk. Gout is a common condition, but it occurs more frequently in some populations than others. For example, gout occurs in 1 percent of people with Asian ancestry, 3 to 4 percent of people with European ancestry, and 6 to 8 percent of Indigenous (native) Taiwanese peoples and Māori from New Zealand.


In about 15 percent of people with gout, urate accumulates in the kidneys
and forms kidney stones . As the condition worsens, urate crystals can also be deposited under the skin or in other soft tissue, forming a nodule called a tophus (plural: tophi). These tophi often form in the hands, elbows, or feet. Tophi do not typically cause pain, but they can become inflamed, infected, or ooze fluid. Depending on their location, tophi can interfere with movements such as walking or gripping objects.

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Gout and Metabolic Disease: Can Probiotics help?

As we know, many studies have linked Gout with chronic inflammation and obesity.  Both conditions contribute a group of factors that increase the risks of heart disease, stroke, and diabetes – also known as metabolic syndrome.  Metabolic syndrome is a cluster of biochemical and physiological abnormalities affecting an estimated 50 million Americans.

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Does Gout Increase The Cardiovascular Disease Risk Factor?

Cardiovascular Disease and Gout

heart disease

The prevalence of cardiovascular disease continues to rise and is among the leading cause of mortality in the world. Inflammatory conditions such as Rheumatoid Arthritis and Gout are often associated with a higher risk and earlier onset of this disease. Research links gout to an increased risk of several types of cardiovascular disease, including heart attack, heart failure, and atrial fibrillation, or an irregular heartbeat. Epidemiological, experimental, and clinical data show that patients with hyperuricemia SUA are at increased risk of cardiac, renal, and vascular damage and CV events. Continue reading “Does Gout Increase The Cardiovascular Disease Risk Factor?”

Gout ‘more than doubles’ risk of kidney failure

Largest ever study on subject uses data from more than 620,000 patients in UK health system


Date: August 28, 2019
Source:University of Limerick
Summary: Patients with gout are at increased risk of chronic kidney disease and kidney failure, according to new research.

Patients with gout are at increased risk of chronic kidney disease and kidney failure, according to new University of Limerick (UL), Ireland led research.

In one of the largest and most detailed studies ever conducted, patients recruited in general practice with a diagnosis of gout were more than twice as likely to develop kidney failure than those without, according to the study led by researchers at University of Limerick’s (UL) Graduate Entry Medical School (GEMS).

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Wearable sweat sensor detects gout-causing compounds

Date:November 25, 2019

Source: California Institute of Technology

Summary: Scientists have developed an easier way to mass-produce highly sensitive sweat sensors that can detect a variety of low-concentration compounds related to health conditions.

There are numerous things to dislike about going to the doctor: Paying a copay, sitting in the waiting room, out-of-date magazines, sick people coughing without covering their mouths. For many, though, the worst thing about a doctor’s visit is getting stuck with a needle. Blood tests are a tried-and-true way of evaluating what is going on with your body, but the discomfort is unavoidable. Or maybe not, say Caltech scientists.

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Artichoke Powder for Gout and Joint Health

ARTICHOKE POWDER (Globe Artichoke)

A relative of the hepatoprotective Milk Thistle, is popular for its pungent taste which is attributed to phytochemicals found in the green parts of the plants called cynaropicrin and cynarin, sesquiterpene lactones with documented medicinal actions. The phytochemicals in artichoke have been well documented and the leaves rather than the flower have been found to be higher in medicinal value.

Artichokes contain a very high antioxidant content, and in fact, contain two compounds (apigenin 7-rutinoside and narirutin) that are so unique they aren’t found in any other plant.

Traditional uses have included support for sluggish liver, poor digestion and atherosclerosis. Artichokes offer concentrated sources of amino acids and even help to support the natural growth of probiotics for the digestive system.

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Gout and Kidney Disease

Chronic kidney disease (CKD)

Chronic kidney disease (CKD) limits the amount of waste filtration your body is capable of processing. Uric acid is not seen as a foreign matter to the body, therefore is usually last to be dealt with from a toxin filtering standpoint. This can allow for uric acid build-up, and, in turn, the increased likelihood of developing Gout. The medications used to treat kidney disease have also been associated with drug-induced cases of Gout. Diuretics and beta blockers are typically used for kidney disease induced high blood pressure and are well known to contribute to Gout development.

There is enough scientific research to confirm that kidney disease can cause Gout. How about the opposite? Can Gout lead to kidney disease? The chicken or the egg? Uric acid is filtered through the kidneys, an undeniable relation to both diseases. While this connection may be less established, the evidence is certainly present. Each condition is well-equipped to feed the other.

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