Does Gout Increase The Cardiovascular Disease Risk Factor?

Cardiovascular Disease and Gout

heart disease

The prevalence of cardiovascular disease continues to rise and is among the leading cause of mortality in the world. Inflammatory conditions such as Rheumatoid Arthritis and Gout are often associated with a higher risk and earlier onset of this disease. Research links gout to an increased risk of several types of cardiovascular disease, including heart attack, heart failure, and atrial fibrillation, or an irregular heartbeat. Epidemiological, experimental, and clinical data show that patients with hyperuricemia SUA are at increased risk of cardiac, renal, and vascular damage and CV events. Continue reading “Does Gout Increase The Cardiovascular Disease Risk Factor?”

Gout ‘more than doubles’ risk of kidney failure

Largest ever study on subject uses data from more than 620,000 patients in UK health system


Date: August 28, 2019
Source:University of Limerick
Summary: Patients with gout are at increased risk of chronic kidney disease and kidney failure, according to new research.

Patients with gout are at increased risk of chronic kidney disease and kidney failure, according to new University of Limerick (UL), Ireland led research.

In one of the largest and most detailed studies ever conducted, patients recruited in general practice with a diagnosis of gout were more than twice as likely to develop kidney failure than those without, according to the study led by researchers at University of Limerick’s (UL) Graduate Entry Medical School (GEMS).

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Wearable sweat sensor detects gout-causing compounds

Date:November 25, 2019

Source: California Institute of Technology

Summary: Scientists have developed an easier way to mass-produce highly sensitive sweat sensors that can detect a variety of low-concentration compounds related to health conditions.

There are numerous things to dislike about going to the doctor: Paying a copay, sitting in the waiting room, out-of-date magazines, sick people coughing without covering their mouths. For many, though, the worst thing about a doctor’s visit is getting stuck with a needle. Blood tests are a tried-and-true way of evaluating what is going on with your body, but the discomfort is unavoidable. Or maybe not, say Caltech scientists.

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Artichoke Powder for Gout and Joint Health

ARTICHOKE POWDER (Globe Artichoke)

A relative of the hepatoprotective Milk Thistle, is popular for its pungent taste which is attributed to phytochemicals found in the green parts of the plants called cynaropicrin and cynarin, sesquiterpene lactones with documented medicinal actions. The phytochemicals in artichoke have been well documented and the leaves rather than the flower have been found to be higher in medicinal value.

Artichokes contain a very high antioxidant content, and in fact, contain two compounds (apigenin 7-rutinoside and narirutin) that are so unique they aren’t found in any other plant.

Traditional uses have included support for sluggish liver, poor digestion and atherosclerosis. Artichokes offer concentrated sources of amino acids and even help to support the natural growth of probiotics for the digestive system.

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Gout and Kidney Stones

Kidney Stones

Kidney Stones (renal calculi) are formed as a result of a buildup of dissolved minerals on the inner lining of the kidneys. Once they make their way into the urinary tract severe pain in the groin, stomach, or flank area can ensue. A decrease in urination coupled with a large amount of stone-forming substances can cause these types of stones to appear. These stones can be formed by the mixture of calcium with oxalate or phosphate; and/or the combination of uric acid and amino acid cysteine.

Much like Gout, Kidney stones are being diagnosed more and more in recent years. The same type of stones can develop in the bladder as well, but are much more uncommon and have remained relatively low and unchanged by comparison. Over the span of almost 30 years, the Mayo Clinic observed a significant rise in the incidences of kidney stones; particularly in adult women. With more accurate CT scans our ability to monitor and diagnose stones are partly behind a good portion of this rise in cases, but also goes hand in hand with the rise in Obesity and Diabetes Type 2. Diets high in sugar, unhealthy fats, and salt have been to blame for stones and this type of diet certainly fits the profile for all of these conditions.

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Gout and Cancer Connection?

Gout and Cancer Connection?

Is there a connection between Gout and Cancer?  Gout is a common inflammatory disease with incidences largely increasing with each passing year and affecting younger and younger age groups  more than ever before.  Acute arthritis and hyperuricemia stems from purine metabolism dysfunction, causing urate crystals to deposit into the tissue leading to kidney stones, soft tissue growths, urate nephropathy and/or arthritis.  Epidemiological studies have been conducted to estimate the potential association between Gout and Cancer risks.  These studies have displayed a preeminent role of Gout in carcinogenesis.

Cellular death and higher turnover rates can bring about hyperuricemia and the formation of tumors (tumorigenesis.)  Even though strong evidence exists to show the connection between high serum uric acid levels and an independent increased risk of cancer, the subject remains disputable. Continue reading “Gout and Cancer Connection?”