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Understanding Uric Acid

Uric Acid

Purines perform multiple important functions within our cells, including regulating energy metabolism and signaling the energy conversion from one to another. Purines are essentially the building blocks for all living things as a necessity for the growth, proliferation and survival of all cells. The two purine bases, adenine and guanine, create bonds that form the DNA ladder. Humans breakdown purines and convert them into uric acid.

Uric acid happens to be a potent DNA protector. All other mammals possess an enzyme known as uricase. Uricase converts uric acid into allantoin, which can easily travel through the bloodstream and readily eliminated through the urine. Humans do not possess this enzyme, therefore, we cannot oxidize uric acid into the more soluble compound of allantoin. Our liver and kidneys are left to do the all-important jobs of purine breakdown and uric acid disposal, conducted respectively.

Cold and Flu Season is Upon Us…………

Are you prepared for the winter germs?

Have you done enough to avoid illness and pain associated with this dreaded season?

Can the cold and flu season raise your threat of a Gout attack?

Can illness increase your arthritic joint pain and inflammation in general?

Contrary to popular belief, you can avoid serious bouts of illness and still avoid the flu shot. Optimizing your health through diet, water, sleep, and supplementation won’t only enhance your health overall, it will enhance your body’s ability to ward or fight off any of those nasty germs surrounding you. Even if you succumb to the germs, you can drastically reduce the severity of the hit with a strengthened immune system. Continue reading “Cold and Flu Season is Upon Us…………”

How to travel and avoid Gout

Traveling can be hectic as is, and downright scary if you suffer from Gout. If you are going abroad it can be even more of a worry as you are not near home, or in the same country to get the help you need, that is why making a packing list, or checking one out from such websites as Rent.is can be very beneficial. Why does Gout tend to attack at THE worst imaginable times and can you avoid this fate?

The anticipation and fear of the next Gout attack can be extremely stressful. Travel can be very stressful, too. Unfortunately, stress can actually CAUSE an attack. Stress can dramatically alter the pH of the body increasing its acid load, pulling minerals from the body, and triggering inflammation. While finally arriving at your destination can be relaxing and fun, the stress leading up to that point could cause problems.

· Try to pack well ahead of time and don’t overthink it. Most people don’t use half of the things they bring. Make a list over a long period of time and stick to it.

· If you are flying, have your documents for security set aside separately and plan to arrive with plenty of time to spare.

· Get plenty of rest, stay hydrated, and eat well (at least leading up to the vacay.)

· Stress and travel can deplete the healthy bacteria in the body. Taking a high quality probiotic before, during, and after travel can help a great deal.

· Breathe deeply and try to relax. Continue reading “How to travel and avoid Gout”

Gout can be found in dogs and other animals

Excessive amounts of uric acid in the bloodstream are not limited to only humans. Gout can affect our loving canine and feline friends, as well. Whereas humans are more likely to experience crystal deposits in the joint extremities, animals tend to grow uric acid crystals in their urine. When animals are unable to assimilate calcium and other minerals, abnormal uric acid and calcium levels can also deposit into the paws, toes, elbows, neck, ears, and tongue. This is know as calcified skin lesions, or Casinosis Cutis, and more common in breeds such as Boxers and Boston Terriers. Calcium “Gout” can also create a chalky liquid that can ooze from the paws. Continue reading “Gout can be found in dogs and other animals”

Is Distilled Water Good or Bad for you?

In a desperate search to consume a safer water source than the parasite, dioxin and chlorine ridden tap water, many resort to distilled water. Contrary to popular belief, distilled water is acidic. Distilled water is boiled until it evaporates. This vapor is then condensed back into liquid form. Hypothetically, distilled water should offer us a neutral pH balance around 7.0 to provide an alkaline and purified drinking source. However, carbon dioxide in the air dissolves into the water immediately upon exposure decreasing the pH and turning it acidic. Additionally, the distillation process strips the water of its minerals and could lead to electrolyte imbalances in the body. When you consume mineral free water over a long period of time the body will pull electrolytes from your tissues in order to function properly and eliminate waste.

Did you know that soda and other soft drinks are made with distilled water? As if soda isn’t already bad enough for us, heavy soda consumers are literally stripping and dumping large amounts of vital minerals (calcium, magnesium, and other trace minerals) into their urine. Mineral loss can quickly lead to any number of degenerative diseases including coronary heart disease, high blood pressure, arrhythmia, osteoarthritis, osteoporosis, hypothyroidism and more. Minerals are essential to our body’s pH balance and acidic environments only speed up aging and disease development. Continue reading “Is Distilled Water Good or Bad for you?”

New evidence of increased risk of death with Febuxostat (Uloric)

According to the latest CARES trial, the Gout drug Febuxostat (Uloric) failed up against Allopurinol when it came down to a combined rate of fatal and nonfatal adverse events for those that suffer with both Gout and Cardiovascular disease. In fact, there was a significant increased risk of death for those that took this drug for Gout while also suffering from heart disease.

The trial was mandated by the FDA and consisted of 6,190 patients, 84% of which were men. Cardiovascular risk is naturally increased in patients with Gout. The study was attempting to look at any difference in outcome for these patients taking Febuxostat, a nonpurine xanthine oxidase inhibitor, or those taking Allopurinol, a purine base analogue xanthine oxidase inhibitor. The patients were followed for a median of 32 months, and a maximum of 85 months. Without diving into all of the ratio statistics, the all-cause and cardiovascular mortality rate was higher in the Febuxostat group, 34% and 22% higher respectively. Continue reading “New evidence of increased risk of death with Febuxostat (Uloric)”

Acetaminophen (Tylenol) and the hidden dangers

Acetaminophen (also labeled as Paracetamol, or more commonly known as Tylenol) is one of the most widely used OTC (over the counter) pain medications on the shelves today. Most of us don’t even think twice about taking something we can readily obtain from a local store when the occasional ache or pain calls for such. However, acetaminophen may just be one of the most dangerous choices on the market. Even when taken as prescribed, acetaminophen can be potentially life-threatening. As with many OTC medications, we tend to be a bit too liberal with dosage recommendations, rarely fearing taking 3 or 4 rather than the suggested 2 pills. When it comes to this pain reliever, failing to adhere to the recommended dosages could prove to be lethal. Severe health problems like liver damage and death have been reported even in so-called “mild” overdoses. In fact, hospitals deal with more acetaminophen overdoses annually than they do opiate overdoses. I can only imagine the shock and dismay, or your utter refusal to believe such a statistic — especially considering you’ve probably never heard of any of this….. Continue reading “Acetaminophen (Tylenol) and the hidden dangers”

Gout, uric acid, and risk of death

Gout affects an estimated 4% of the population, or around 1 in 25 people. Evidence suggests this number is growing and is certainly affecting a larger demographic than in the past. A lot of confusion has surrounded the specifics on how high levels of uric acid may affect the heart and kidneys, even when acute Gout attacks are not present.

There have been studies attempting to separate the mortality rates of those with other risk factors, namely cardiovascular disease and diabetes, from those with just Gout and/or high uric acid levels. The findings seem to suggest that Gout and high uric acid levels are independently responsible for higher death rates across most age, sex, and race subgroups independent of other pre-existing conditions. The University in Limerick found those with the high serum uric acid levels displayed at 77% higher risk of death from all causes, and a 209% higher risk of cardiovascular death. While pre-existing conditions such as obesity, hypertension, diabetes, etc. are strongly associated with a higher death risk, the results did not decrease by much when those factors were removed.

What does this mean for the Gout sufferer? Continue reading “Gout, uric acid, and risk of death”

Is Soy Good or Bad?

Soy can provide a significant amount of protein, vitamins, minerals and polyunsaturated fatty acids. The soybean is also a source of resveratrol, phytosterols, and isoflavones — all of which have been scientifically linked to providing benefits for a number of health conditions.

However, there is a dark side to soy, particularly unfermented soy products – dark enough to consider its inherent dangers to outweigh its benefits. The Weston A. Price Foundation is a valuable source for accurate information about our nutrition and health. They are dedicated to putting nutrient-dense foods back on our tables and have done a great job researching this subject to provide us with the truth and myths about soy. Their website contains numerous studies, over several years, should you be interested diving in a bit deeper. Weston A. Price summarizes soy dangers, myths, and truths as follow: Continue reading “Is Soy Good or Bad?”

Low-fat Diet Myths and Our Deteriorating Health

Is it just a coincidence that ever since we adopted low-fat and fat-free diet plans our health deteriorated? The craze began back in the 70’s and 80’s, and by the early 90’s foods with little to no fat were flying off the shelves. The American Heart Association, food manufacturers, physicians, and even drug manufacturers had convinced us that all saturated fats led to obesity and heart disease. People began trading nuts for pretzels, whole milk for skim, potatoes -hold the sour cream, and even still buying cookies so long as they were labeled “fat free.” Dietary fats and all cholesterol were deemed to be bad for our health. Yet, over this same 30+ year time span of ‘healthier’ eating the incidences of obesity, diabetes and cardiovascular disease have soared to alarming rates. In addition to all of the fat-free products flying off of the shelves, so have the cholesterol-lowering and blood pressure lowering drugs.

So wait…… Continue reading “Low-fat Diet Myths and Our Deteriorating Health”

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